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IGF-1 LR3

Insulin-like Growth Factor-1 Long R3 • Also called IGF1-LR3, IGF 1 LR3, Long R3 IGF-1

Restricted

IGF-1 LR3 remains a staple search term in bodybuilding and biohacking markets, but FDA has treated compounded products using it as lacking a qualifying 503A basis.

Current status

Restricted

Growth- and recovery-related interest, with current federal compounding constraints still in play.

FDA category

Not on 503A bulks list

Can pharmacies compound this?

No

Reclassification expected?

Unclear

The current issue is not a near-term review queue. FDA has already described compounded IGF1-LR3 products as ineligible for the usual 503A exemptions.

Primary Use

Growth- and recovery-related interest

muscle-related interestrecovery-related interestperformance interest

Also searched as

IGF1-LR3, IGF 1 LR3, Long R3 IGF-1

Regulatory Timeline

Feb 27, 2026

Political pressure and market expectations increased around a future peptide reclassification review.

Mar 15, 2023

FDA peptide compounding scrutiny intensified across 503A and 503B channels.

Apr 1, 2020

Current status signal recorded: FDA warning-letter posture says it is not the subject of an applicable USP or NF monograph, is not a component of an FDA-approved human drug, and does not appear on the 503A bulks list..

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State-specific notes

Ohio

High-risk performance peptides tend to disappear quickly from compliant sourcing channels.