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LL-37

Cathelicidin LL-37

Restricted

LL-37 is associated with antimicrobial and immune claims, but it remains on the restricted side of the current peptide landscape.

Current status

Restricted

Immune-related interest, with current federal compounding constraints still in play.

FDA category

Category 2

Can pharmacies compound this?

No

Reclassification expected?

Unclear

Less visible in reclassification chatter than other peptides in this group.

Primary Use

Immune-related interest

immune-related interestinjury-related interestrecovery-related interest

Regulatory Timeline

Feb 27, 2026

Political pressure and market expectations increased around a future peptide reclassification review.

Sep 29, 2023

Current status signal recorded: Remains on the restricted list with limited public momentum for change..

Mar 15, 2023

FDA peptide compounding scrutiny intensified across 503A and 503B channels.

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State-specific notes

California

Risk tolerance is especially low for immune peptides.